Similar finding was observed in a previous study, which aimed to characterize customers dispensed pregabalin at higher than the maximum allowed dose based on data extracted from Swedish national registers (Bodén et al., 2014). In this cohort study, a higher pregabalin strengths, were the most concentrations reported (Bodén et al., 2014). Stokes Healthcare has prepared medications for your individual patients since 1975 through Stokes Pharmacy.

• If you experience memory loss or other cognitive symptoms while taking pregabalin, inform your healthcare provider, as they may need to adjust your dosage or explore alternative treatment options.
• Next came a dual GLP-1/GIP receptor agonist, tirzepatide, marketed under the brand name Zepbound, which was approved for obesity in 2023.
• If you have lung or breathing problems, discuss the potential risks with your healthcare provider before beginning pregabalin (Lyrica) treatment.
• In these suspected cases pregabalin concentrations of abuse were 150 mg in 18 cases.
• This study was conducted to provide background data regarding the abuse/misuse of pregabalin from community pharmacy in Jordan.

What are the differences between OTC and prescription weight loss medications?

So efforts are needed to support the addition of this drug to the controlled drug list (which can’t be purchased without prescription in Jordan). In order to support this requirement, we aimed in this observational study to provide background data regarding the abuse/misuse of pregabalin products in a community pharmacy setting in Jordan. Up to the researchers’ knowledge, this is the first study of its kind in Jordan to address this issue. Amgen is developing maridebart cafraglutide, known as MariTide, a long-acting peptide-antibody conjugate designed to increase GLP-1 receptor activity while inhibiting GIP receptor activity. The once-monthly injection entered phase 3 clinical trials for weight loss and type 2 diabetes in March 2025.

Pregabalin may interact with other medications

Future studies will investigate the effect of MariTide on cardiovascular disease, heart failure, chronic kidney disease, and obstructive sleep apnea. In a phase 2 study, the medication showed up to 20% average weight loss at 52 weeks for people with obesity or overweight without diabetes and 17% for those with overweight/obesity and type 2 diabetes. All these findings call the attention for implementation of effective community pharmacy based interventions to raise customer, neurologist and pharmacist awareness and ultimately reduce the abuse rate of pregabalin products. Also, these findings should support the appeal for the addition of pregabalin preparations to controlled drugs list (which can’t be purchased without prescription in Jordan). One of the strengths of this study is the prospective observation on real cases in a community pharmacy setting. In this study customers-pharmacist interactions involving pregabalin products were observed at different community pharmacies in Amman.

Those of targets center around nutrient-sensing hormones including GLP-1, GIP, glucagon, amylin, peptide tyrosine-tyrosine (PYY) and cholecystokinin (CCK). Klinic’s experienced providers can help you navigate these warnings and determine if pregabalin (Lyrica) is the right choice for your unique health needs. Our personalized approach to care ensures that you receive a comprehensive evaluation and ongoing support throughout your treatment journey. A convenience sampling technique was used to select the involved pharmacis. This was based on the feasibility, geographical proximity to the researchers housing, and upon consenting to participate by the pharmacy manager of each community pharmacy. Researchers took every effort to cover most socioeconomic regions in Amman (Dahiyat ALrasheed, Al-Jandaweel, Sweifieh, Sweileh, cost of lyrica Khalda, Jbeiha, Sahab, Wadi-Alseir, Khrbet Alsouq, and Arjan).